Relationship between Two Types of Coil Packing Densities Relative to Aneurysm Size

J Neuroimaging. 2015 May-Jun;25(3):415-9. doi: 10.1111/jon.12140. Epub 2014 Jul 15.

Abstract

Background and purpose: Coil packing density (PD) can be calculated via a formula (PDF ) or software (PDS ). Two types of PD can be different from each other for same aneurysm. This study aimed to evaluate the interobserver agreement and relationships between the 2 types of PD relative to aneurysm size.

Methods: Consecutive 420 saccular aneurysms were treated with coiling. PD (PDF , [coil volume]/[volume calculated by formula] and PDS, [coil volume]/[volume measured by software]) was calculated and prospectively recorded. Interobserver agreement was evaluated between PDF and PDS . Additionally, the relationships between PDF and PDS relative to aneurysm size were subsequently analyzed.

Results: Interobserver agreement for PDF and PDS was excellent (Intraclass correlation coefficient, PDF ; 0.967 and PDS ; 0.998). The ratio of PDF and PDS was greater for smaller aneurysms and converged toward 1.0 as the maximum dimension (DM ) of aneurysm increased. Compared with PDS , PDF was overestimated by a mean of 28% for DM < 5 mm, by 17% for 5 mm ≤ DM < 10 mm, and by 9% for DM ≥ 10 mm (P < 0.01).

Conclusions: Interobserver agreement for PDF and PDS was excellent. However, PDF was overestimated in smaller aneurysms and converged to PDS as aneurysm size increased.

Keywords: Aneurysm; coiling; packing density.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebral Angiography / methods*
  • Embolization, Therapeutic / instrumentation
  • Embolization, Therapeutic / methods*
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Intracranial Aneurysm / diagnostic imaging*
  • Intracranial Aneurysm / therapy*
  • Observer Variation
  • Prognosis
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Treatment Outcome