Astrocyte morphology is controlled by neuron-derived FGF

Amit Agarwal; Dwight E Bergles

doi:10.1016/j.neuron.2014.07.005

Astrocyte morphology is controlled by neuron-derived FGF

Neuron. 2014 Jul 16;83(2):255-257. doi: 10.1016/j.neuron.2014.07.005.

Authors

Amit Agarwal¹, Dwight E Bergles²

Affiliations

¹ Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
² Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA. Electronic address: dbergles@jhmi.edu.

Abstract

The highly ramified processes of astrocytes enable cellular interactions and extracellular homeostasis. In this issue of Neuron, Stork et al. (2014) report that extension and elaboration of astrocyte processes in Drosophila is controlled by the release of FGF by neurons.

Publication types

Comment

MeSH terms

Animals
Astrocytes / metabolism*
Cell Communication / physiology*
Drosophila Proteins / metabolism*
Morphogenesis / physiology*
Neurons / metabolism*
Protein-Tyrosine Kinases / metabolism*
Receptors, Fibroblast Growth Factor / metabolism*
Signal Transduction / physiology*

Substances

Drosophila Proteins
Receptors, Fibroblast Growth Factor
Protein-Tyrosine Kinases
htl protein, Drosophila

Grants and funding

P50 MH100024/MH/NIMH NIH HHS/United States