Abstract
(18)F-fluorodihydroxyphenylalanine (FDOPA) is a powerful tool for the diagnosis and detection of neuroendocrine tumors when planning and monitoring surgical and oncologic therapies. Pheochromocytomas, paragangliomas, and medullary thyroid cancers especially are amenable to FDOPA imaging because of the high specific uptake of this amino acid analogue and excellent tumor-to-background contrast on PET/computed tomography.
Keywords:
(18)F-Fluorodihydroxyphenylalanine; Medullary thyroid cancer; Neuroendocrine tumor; PET/computed tomography; Pheochromocytoma.
Copyright © 2014 Elsevier Inc. All rights reserved.
MeSH terms
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Adrenal Gland Neoplasms / diagnostic imaging
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Carcinoma, Neuroendocrine
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Dihydroxyphenylalanine / analogs & derivatives*
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Humans
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Intestinal Neoplasms / diagnostic imaging
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Neuroendocrine Tumors / diagnostic imaging*
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Pancreatic Neoplasms / diagnostic imaging
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Paraganglioma / diagnostic imaging
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Pheochromocytoma / diagnostic imaging
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Positron-Emission Tomography / methods*
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Radiopharmaceuticals*
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Stomach Neoplasms / diagnostic imaging
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Thyroid Neoplasms / diagnostic imaging
Substances
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Radiopharmaceuticals
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fluorodopa F 18
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Dihydroxyphenylalanine
Supplementary concepts
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Gastro-enteropancreatic neuroendocrine tumor
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Thyroid cancer, medullary