Single-photon emission computed tomography tracers in the diagnostics of neuroendocrine tumors

PET Clin. 2014 Jan;9(1):11-26. doi: 10.1016/j.cpet.2013.08.011. Epub 2013 Oct 4.

Abstract

Different imaging strategies have been developed targeting the peculiar features of neuroendocrine tumors (NETs). Metabolic characteristics and receptor expression on the tumor surface have been studied, and expertise and knowledge are increasing as a result of the implementation of fusion imaging and the development of more detailed positron emission tomography tracers. Scintigraphic study of NETs is the most diffused and convenient technique for evaluating patients suspected to have NETs.

Keywords: Pentetreotide; Somatostatin; Somatostatin analogues; mIBG.

Publication types

  • Review

MeSH terms

  • 3-Iodobenzylguanidine*
  • Adrenal Gland Neoplasms / diagnostic imaging
  • Carcinoma, Neuroendocrine
  • Contraindications
  • Humans
  • Intestinal Neoplasms / diagnostic imaging
  • Lung Neoplasms / diagnostic imaging
  • Neuroblastoma / diagnostic imaging
  • Neuroendocrine Tumors / diagnostic imaging*
  • Pancreatic Neoplasms / diagnostic imaging
  • Paraganglioma / diagnostic imaging
  • Pheochromocytoma / diagnostic imaging
  • Pituitary Neoplasms / diagnostic imaging
  • Radiopharmaceuticals*
  • Receptors, Somatostatin / metabolism
  • Somatostatin / analogs & derivatives*
  • Stomach Neoplasms / diagnostic imaging
  • Thyroid Neoplasms / diagnostic imaging
  • Tomography, Emission-Computed, Single-Photon / methods*
  • Tomography, Emission-Computed, Single-Photon / trends

Substances

  • Radiopharmaceuticals
  • Receptors, Somatostatin
  • 3-Iodobenzylguanidine
  • Somatostatin

Supplementary concepts

  • Gastro-enteropancreatic neuroendocrine tumor
  • Thyroid cancer, medullary