Programmed stereoselective assembly of DNA-binding helical metallopeptides

Chem Commun (Camb). 2014 Oct 4;50(76):11097-100. doi: 10.1039/c4cc03606a.

Abstract

A flexible and versatile synthetic approach for the construction of water-stable DNA-binding chiral peptide helicates based on the solid phase peptide synthesis (SPPS) methodology is reported.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • DNA / chemistry*
  • Metalloproteins / chemistry*
  • Models, Molecular
  • Molecular Structure
  • Stereoisomerism
  • Water / chemistry

Substances

  • Metalloproteins
  • Water
  • DNA