Sediment cytology in diagnostic evaluation of oral neoplasms

Indian J Dent Res. 2014 Mar-Apr;25(2):147-9. doi: 10.4103/0970-9290.135904.

Abstract

Aim: To evaluate the role of sediment cytology of biopsy specimen fixatives in early diagnosis of oral neoplasms.

Materials and methods: Cytological smears were prepared by centrifuging the fixatives in which the biopsy specimens were received. The smears were analyzed and the cytological results were compared with histological diagnosis.

Results: Of 20 lesions studied by sediment cytology, 8 were labeled as benign, 9 as malignant and 3 cases as inconclusive. Final histopathological diagnosis labeled 12 lesions as malignant and 8 lesions as benign. Comparing the cytological diagnosis with histological sections, 17 out of 20 cases were concordant. The overall diagnostic accuracy of 85% was achieved.

Conclusion: Biopsy sediment cytology is a good complimentary method to histopathology in the study of oral biopsy material.

MeSH terms

  • Biopsy
  • Humans
  • Mouth Neoplasms / classification
  • Mouth Neoplasms / diagnosis*
  • Mouth Neoplasms / pathology
  • Sensitivity and Specificity