Candida vascular complication in a liver transplant recipient due to yeast contamination of preservation solution

Transpl Infect Dis. 2014 Oct;16(5):827-9. doi: 10.1111/tid.12260. Epub 2014 Jul 1.

Abstract

Infections remain a major cause of morbidity and mortality after liver transplantation. One possible cause of infection is preservation fluid contamination. Donor-derived pathogens, such as Candida albicans, have occasionally produced life-threatening complications in organ recipients, already described in renal transplantation. In the present case, we report the loss of a liver graft secondary to vascular complications because of C. albicans found in the preservation fluid. Our case report raises the question of implementing procedures, similar to those in renal transplantation, including early antifungal treatment and repeated radiological monitoring for the prevention and detection of vascular complications.

Keywords: Candida albicans; aneurysm; fungal infection; liver transplantation; preservation solution; vascular complications.

Publication types

  • Case Reports

MeSH terms

  • Candida albicans
  • Candidiasis / complications*
  • Fatal Outcome
  • Graft Rejection / immunology
  • Humans
  • Liver Transplantation / adverse effects*
  • Liver*
  • Male
  • Middle Aged
  • Organ Preservation Solutions / adverse effects*
  • Peritonitis / microbiology
  • Shock, Septic / microbiology*
  • Vascular Diseases / microbiology*

Substances

  • Organ Preservation Solutions