Asymmetric oro-facial angioedema following alteplase for acute ischaemic stroke

Teddy Y Wu; Diana Y Wei; Yvette Baker; Brendan Sharkey; Richard W Frith

doi:10.1016/j.jocn.2014.03.023

Asymmetric oro-facial angioedema following alteplase for acute ischaemic stroke

J Clin Neurosci. 2014 Nov;21(11):2004-6. doi: 10.1016/j.jocn.2014.03.023. Epub 2014 Jun 25.

Authors

Teddy Y Wu¹, Diana Y Wei², Yvette Baker², Brendan Sharkey², Richard W Frith²

Affiliations

¹ Department of Neurology, Auckland City Hospital, Park Road, Grafton, Private Bag 92024, Auckland 1142, New Zealand. Electronic address: teddyyhwu@gmail.com.
² Department of Neurology, Auckland City Hospital, Park Road, Grafton, Private Bag 92024, Auckland 1142, New Zealand.

PMID: 24974191
DOI: 10.1016/j.jocn.2014.03.023

Abstract

We present a patient with asymmetric oro-facial angioedema following thrombolysis for acute ischaemic stroke with serial photographs of this phenomenon. We discuss the mechanism for the development of asymmetric oro-facial oedema following thrombolysis and suggest a management plan.

Keywords: Angioedema; Stroke; Thrombolysis.

Publication types

Case Reports

MeSH terms

Aged, 80 and over
Angioedema / chemically induced*
Angioedema / therapy
Bradykinin / drug effects
Bradykinin / metabolism
Brain Ischemia / complications*
Face / pathology*
Fibrinolytic Agents / administration & dosage
Fibrinolytic Agents / adverse effects*
Humans
Male
Stroke / drug therapy*
Stroke / etiology
Tissue Plasminogen Activator / administration & dosage
Tissue Plasminogen Activator / adverse effects*

Substances

Fibrinolytic Agents
Tissue Plasminogen Activator
Bradykinin