TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites

Cell Res. 2014 Aug;24(8):1017-20. doi: 10.1038/cr.2014.81. Epub 2014 Jun 27.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 5-Methylcytosine / chemistry
  • 5-Methylcytosine / metabolism*
  • Animals
  • Biocatalysis
  • DNA Methylation / drug effects
  • Dioxygenases / metabolism*
  • Gene Expression Regulation
  • Glucose / pharmacology
  • Glutamic Acid / pharmacology
  • Glutamine / pharmacology
  • Hydroxylation
  • Ketoglutaric Acids / metabolism
  • Liver / enzymology
  • Liver / metabolism
  • Mice

Substances

  • Ketoglutaric Acids
  • Glutamine
  • Glutamic Acid
  • 5-Methylcytosine
  • Dioxygenases
  • Glucose