Two new flavonols from Cudrania cochinchinensis

J Asian Nat Prod Res. 2014 Oct;16(10):976-81. doi: 10.1080/10286020.2014.923843. Epub 2014 Jun 23.

Abstract

Two new flavonols, 6-p-hydroxybenzyl kaempferol (1) and 6-p-hydroxybenzyl quercetin (2), together with six known compounds were isolated from the roots of Cudrania cochinchinensis and their structures elucidated on the basis of spectroscopic methods. Their antioxidant capacities were evaluated by 1,1-diphenyl-2-picryl-hydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical-scavenging assays. The results suggested that compounds 2, 4, and 7 showed significant radical-scavenging activities.

Keywords: 6-p-hydroxybenzyl quercetin; 6-p-hydroxybenzylkaempferol; Cudrania cochinchinensis; antioxidant activity; flavonols.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology
  • Biphenyl Compounds / pharmacology
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / pharmacology
  • Flavonols / chemistry
  • Flavonols / isolation & purification*
  • Flavonols / pharmacology
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Free Radical Scavengers / pharmacology
  • Kaempferols / chemistry
  • Kaempferols / isolation & purification*
  • Kaempferols / pharmacology
  • Molecular Structure
  • Moraceae / chemistry*
  • Picrates / pharmacology
  • Plant Roots / chemistry
  • Quercetin / analogs & derivatives*
  • Quercetin / chemistry
  • Quercetin / isolation & purification
  • Quercetin / pharmacology

Substances

  • 6-p-hydroxybenzyl kaempferol
  • 6-p-hydroxybenzyl quercetin
  • Antioxidants
  • Biphenyl Compounds
  • Drugs, Chinese Herbal
  • Flavonols
  • Free Radical Scavengers
  • Kaempferols
  • Picrates
  • Quercetin
  • 1,1-diphenyl-2-picrylhydrazyl