The use of inert gas xenon for cryopreservation of leukocytes

D S Laptev; T V Polezhaeva; O O Zaitseva; A N Khudyakov; O N Solomina; S V Utemov

doi:10.1007/s10517-014-2545-6

The use of inert gas xenon for cryopreservation of leukocytes

Bull Exp Biol Med. 2014 Jun;157(2):282-4. doi: 10.1007/s10517-014-2545-6. Epub 2014 Jun 22.

Authors

D S Laptev¹, T V Polezhaeva, O O Zaitseva, A N Khudyakov, O N Solomina, S V Utemov

Affiliation

¹ Laboratory of Blood Cryophysiology, Institute of Physiology, Komi Research Center, Ural Division of the Russian Academy of Sciences, Syktyvkar, Russia.

PMID: 24952499
DOI: 10.1007/s10517-014-2545-6

Abstract

We studied the possibility of cryopreservation of human blood nuclear cells under protection with inert gas xenon. A method for inducing clathrate anabiosis of leukocytes was developed that preserved the cells for practical use in biology and medicine.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cells, Cultured
Cryopreservation / methods*
Humans
Leukocytes / drug effects*
Terpenes / metabolism
Xenon / pharmacology*

Substances

Terpenes
clathric acid
Xenon