Does the ORF in the control region of Mytilus mtDNA code for a protein product?

Eleni Kyriakou; Evanthia Chatzoglou; George C Rodakis; Eleftherios Zouros

doi:10.1016/j.gene.2014.06.031

Does the ORF in the control region of Mytilus mtDNA code for a protein product?

Gene. 2014 Aug 10;546(2):448-50. doi: 10.1016/j.gene.2014.06.031. Epub 2014 Jun 18.

Authors

Eleni Kyriakou¹, Evanthia Chatzoglou¹, George C Rodakis¹, Eleftherios Zouros²

Affiliations

¹ Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Panepistimioupolis 15701 Athens, Greece.
² Department of Biology, University of Crete, 71409 Heraklion, Crete, Greece. Electronic address: zouros@biology.uoc.gr.

PMID: 24950231
DOI: 10.1016/j.gene.2014.06.031

Abstract

The control region of the mtDNA of Mytilus is known to contain sequences that determine whether the genome will be paternally or maternally transmitted. An open reading frame (ORF) in this region raised suspicion that it may code for a protein involved in this mechanism. An analysis of the mtDNA transcriptome failed to produce evidence for this hypothesis.

Keywords: Bivalvia; Doubly uniparental inheritance; Mytilus; mtDNA control region; mtRNA degradation.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
DNA, Mitochondrial / genetics*
Female
Genome, Mitochondrial / physiology*
Male
Mytilus / genetics*
Open Reading Frames / physiology*

Substances

DNA, Mitochondrial