[Study on drug properties of components in Euodiae Fructus based on rat stress gastric ulcer model with cold syndrome]

Zhongguo Zhong Yao Za Zhi. 2014 Feb;39(3):498-502.
[Article in Chinese]

Abstract

Objective: To clarify drug properties of components in Euodiae Fructus.

Method: The rat cold syndrome model was induced by cold water stress method. The content of neurotransmitters sand hormones such as DA, 5-HT, NE, AChE and 17-OHCS in serum of model rats were taken as the indexes to evaluate drug properties of components in Euodiae Fructus.

Result: Euodiae Fructus and its components could correct or relief the content of energy metabolism and substance metabolism-related neurotransmitters sand hormones in serum of model rats with water-stressed cold syndrome.

Conclusion: Euodiae Fructus and its components are proved to show hot property.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Cold Temperature / adverse effects*
  • Disease Models, Animal
  • Drugs, Chinese Herbal / pharmacology
  • Drugs, Chinese Herbal / therapeutic use
  • Female
  • Gastric Mucosa / drug effects
  • Gastric Mucosa / pathology
  • Male
  • Medicine, Chinese Traditional
  • Neurotransmitter Agents / blood
  • Rats
  • Rats, Wistar
  • Stomach Ulcer / blood
  • Stomach Ulcer / drug therapy*
  • Stomach Ulcer / physiopathology*
  • Stress, Physiological*

Substances

  • Drugs, Chinese Herbal
  • Neurotransmitter Agents
  • wuzhuyu broth