Recent research trends of radio-frequency biosensors for biomolecular detection

Hee-Jo Lee; Jong-Gwan Yook

doi:10.1016/j.bios.2014.05.025

Recent research trends of radio-frequency biosensors for biomolecular detection

Biosens Bioelectron. 2014 Nov 15:61:448-59. doi: 10.1016/j.bios.2014.05.025. Epub 2014 May 21.

Authors

Hee-Jo Lee¹, Jong-Gwan Yook²

Affiliations

¹ School of Electrical and Electronic Engineering, Yonsei University, Seoul, South Korea.
² School of Electrical and Electronic Engineering, Yonsei University, Seoul, South Korea. Electronic address: jgyook@yonsei.ac.kr.

PMID: 24934746
DOI: 10.1016/j.bios.2014.05.025

Abstract

This article reviews radio-frequency (RF) biosensors based on passive and/or active devices and circuits. In particular, we focus on RF biosensors designed for detection of various biomolecules such as biotin-streptavidin, DNA hybridization, IgG, and glucose. The performance of these biosensors has been enhanced by the introduction of various sensing schemes with diverse nanomaterials (e.g., carbon nanotubes, graphene oxide, magnetic and gold nanoparticles, etc.). In addition, the RF biosensing platforms that can be associated with an RF active system are discussed. Finally, the challenges of RF biosensors are presented and suggestions are made for their future direction and prospects.

Keywords: Biomolecule; Biosensor; Detectable limit; Diagnosis; Radio-frequency.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Biosensing Techniques / instrumentation*
Biosensing Techniques / methods
Biotin / analysis
Equipment Design
Glucose / analysis
Humans
Immunoglobulin G / analysis
Nucleic Acid Hybridization / methods
Radio Waves
Streptavidin / analysis
Transducers

Substances

Immunoglobulin G
Biotin
Streptavidin
Glucose