[Gastroesophageal reflux disease model]

A É Lychkova; Iu V Vasil'ev; A V Limantsev; V S Pankrashin; A M Puzikov

[Gastroesophageal reflux disease model]

Eksp Klin Gastroenterol. 2013:(9):52-3.

[Article in Russian]

Authors

A É Lychkova, Iu V Vasil'ev, A V Limantsev, V S Pankrashin, A M Puzikov

PMID: 24933966

Abstract

The model of gastroesophageal reflux disease by administration of 0.2-0.25 ml of a 1% solution of methylene blue to fundal division of rat stomach was created. After 1-5 minutes electromotor activity of the lower third of the esophagus was observed. Mucosa staining was noted.

Publication types

English Abstract

MeSH terms

Animals
Disease Models, Animal*
Enzyme Inhibitors / pharmacology
Esophagus / pathology
Esophagus / physiopathology
Female
Gastroesophageal Reflux* / pathology
Gastroesophageal Reflux* / physiopathology
Humans
Male
Methylene Blue / pharmacology
Rats

Substances

Enzyme Inhibitors
Methylene Blue