Abdominal subcutaneous and visceral fat thickness in newborns: correlation with anthropometric and metabolic profile

J Perinatol. 2014 Dec;34(12):932-5. doi: 10.1038/jp.2014.110. Epub 2014 Jun 5.

Abstract

Objective: To correlate abdominal subcutaneous and visceral fat thickness with anthropometric data and metabolic profile in newborns.

Study design: A cross-sectional study with 99 newborns was performed at Instituto de Medicina Integral Professor Fernando Figueira, Brazil. Abdominal subcutaneous and visceral thickness were measured by ultrasound. Glucose, insulin, homeostatic model assessment-insulin resistance (HOMA-IR), total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, very-low-density lipoprotein cholesterol and triglycerides were determined. Pearson correlation coefficients were calculated.

Result: Abdominal subcutaneous fat thickness was positively correlated with birth weight (r=0.31; P<0.001), height (r=0.27; P<0.001) and abdominal circumference (r=0.26; P<0.001), but not with metabolic profile. Abdominal visceral fat thickness was correlated with abdominal circumference (r=0.23; P=0.01), insulin (r=0.21; P=0.04) and HOMA (r=0.24; P=0.02). The results remained the same among males and females.

Conclusion: Abdominal fat distribution in newborns has a different correlation with anthropometric and metabolic profile. Abdominal subcutaneous fat thickness is positively correlated with anthropometric data whereas abdominal visceral fat thickness is correlated with insulin and HOMA-IR.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Body Composition / physiology
  • Cholesterol / analysis
  • Cross-Sectional Studies
  • Female
  • Humans
  • Infant, Newborn / physiology*
  • Insulin Resistance / physiology
  • Intra-Abdominal Fat / diagnostic imaging
  • Intra-Abdominal Fat / metabolism
  • Intra-Abdominal Fat / physiology*
  • Male
  • Subcutaneous Fat, Abdominal / diagnostic imaging
  • Subcutaneous Fat, Abdominal / metabolism
  • Subcutaneous Fat, Abdominal / physiology*
  • Ultrasonography
  • Waist Circumference / physiology

Substances

  • Cholesterol