Metal-free, efficient oxyfluorination of olefins for the synthesis of α-fluoroketones

Qiang Yang; Liu-Liang Mao; Bin Yang; Shang-Dong Yang

doi:10.1021/ol501357w

Metal-free, efficient oxyfluorination of olefins for the synthesis of α-fluoroketones

Org Lett. 2014 Jul 3;16(13):3460-3. doi: 10.1021/ol501357w. Epub 2014 Jun 5.

Authors

Qiang Yang¹, Liu-Liang Mao, Bin Yang, Shang-Dong Yang

Affiliation

¹ State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, P. R. China.

PMID: 24901370
DOI: 10.1021/ol501357w

Abstract

A novel oxyfluorination of olefin reactions has been developed. The reactions involve a metal-free and green catalytic system for the synthesis of α-fluoroketones which is an important building block for organic synthesis. Moreover, this reaction system exhibits great functional group tolerance.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkenes / chemistry*
Catalysis
Hydrocarbons, Fluorinated / chemical synthesis*
Hydrocarbons, Fluorinated / chemistry
Ketones / chemical synthesis*
Ketones / chemistry
Molecular Structure
Stereoisomerism

Substances

Alkenes
Hydrocarbons, Fluorinated
Ketones