Two-photon-responsive supramolecular hydrogel for controlling materials motion in micrometer space

Tatsuyuki Yoshii; Masato Ikeda; Itaru Hamachi

doi:10.1002/anie.201404158

Two-photon-responsive supramolecular hydrogel for controlling materials motion in micrometer space

Angew Chem Int Ed Engl. 2014 Jul 7;53(28):7264-7. doi: 10.1002/anie.201404158. Epub 2014 May 27.

Authors

Tatsuyuki Yoshii¹, Masato Ikeda, Itaru Hamachi

Affiliation

¹ Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto 615-8510, (Japan).

PMID: 24866821
DOI: 10.1002/anie.201404158

Abstract

Spatiotemporal control of fluidity inside a soft matrix by external stimuli allows real-time manipulation of nano/micromaterials. In this study, we report a two-photon-responsive peptide-based supramolecular hydrogel, the fluidity of which was dramatically controlled with high spatial resolution (10 μm×10 μm×10 μm). The off-on switching of the Brownian motion of nanobeads and chemotaxis of bacteria by two-photon excitation was successfully demonstrated.

Keywords: gels; photochemistry; self-assembly; supramolecular chemistry.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacteria / metabolism
Bacteriological Techniques / instrumentation*
Chemotaxis
Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry*
Molecular Structure
Motion*
Nanocapsules / chemistry
Photons*

Substances

Nanocapsules
Hydrogel, Polyethylene Glycol Dimethacrylate