The future of pharmacotherapy for obsessive-compulsive disorder may lie in a better understanding of its heterogeneity

Expert Opin Pharmacother. 2014 Jul;15(10):1321-3. doi: 10.1517/14656566.2014.924506. Epub 2014 May 28.

Abstract

Pharmacological treatments currently available to treat obsessive-compulsive disorder (OCD) rarely produce remission. This Editorial aims to encourage more targeted research based on the specific OCD symptoms patients primarily present with. Specific OCD symptoms have been associated with distinct clinical characteristics, aetiological hypotheses and treatment responses. Treatment studies should use these findings to develop more targeted pharmacotherapy for patients with OCD.

Keywords: obsessive–compulsive disorder; pharmacotherapy; subtypes.

Publication types

  • Editorial

MeSH terms

  • Antipsychotic Agents / therapeutic use*
  • Drug Therapy, Combination
  • Humans
  • Obsessive-Compulsive Disorder / drug therapy*
  • Obsessive-Compulsive Disorder / physiopathology
  • Obsessive-Compulsive Disorder / psychology
  • Selective Serotonin Reuptake Inhibitors / therapeutic use*

Substances

  • Antipsychotic Agents
  • Serotonin Uptake Inhibitors