Construction of stable chainlike Au nanostructures via silica coating and exploration for potential photothermal therapy

Zhen Yin; Wei Zhang; Qiang Fu; Hua Yue; Wei Wei; Pei Tang; Wenjing Li; Weizhen Li; Lili Lin; Guanghui Ma; Ding Ma

doi:10.1002/smll.201400474

Construction of stable chainlike Au nanostructures via silica coating and exploration for potential photothermal therapy

Small. 2014 Sep 24;10(18):3619-24. doi: 10.1002/smll.201400474. Epub 2014 May 26.

Authors

Zhen Yin¹, Wei Zhang, Qiang Fu, Hua Yue, Wei Wei, Pei Tang, Wenjing Li, Weizhen Li, Lili Lin, Guanghui Ma, Ding Ma

Affiliation

¹ State Key Laboratory of Hollow Fiber, Membrane Materials and Processes, Department of Chemical Engineering, Tianjin Polytechnic University, Tianjin, 300387, China.

PMID: 24861373
DOI: 10.1002/smll.201400474

Abstract

A facile one-pot approach is successfully developed to construct the stable Au nanochains with silica shell via self-assembly and classical Stöber process. The resulting Au chain@SiO2 nanoparticles holds great promise for serving as a safe, reusable, and high-performance photothermal agent against cancer.

Keywords: Au nanoparticles; photothermal therapy; plasmonic effect; self-assembly; silica-coating.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents / chemistry
Colloids / chemistry
Drug Design
Gold / chemistry*
Hep G2 Cells
Humans
Hyperthermia, Induced / methods
Metal Nanoparticles / chemistry*
Nanotechnology / methods
Neoplasms / therapy
Particle Size
Phototherapy / methods*
Solvents / chemistry
Spectrophotometry, Ultraviolet

Substances

Antineoplastic Agents
Colloids
Solvents
Gold