Antibacterial and antiyeast compounds from marine-derived bacteria

Mar Drugs. 2014 May 13;12(5):2913-21. doi: 10.3390/md12052913.

Abstract

Two new (2 and 3) and a known (1) antimicrobial compounds were isolated from EtOAc extracts of two marine bacterial strains cultured in modified Bennett's broth medium. The structures of these compounds were determined based on the analysis of nuclear magnetic resonance (NMR), high resolution mass spectroscopy (HRMS), literature data review and considering biogenesis. All the compounds (1-3) demonstrated in vitro antimicrobial activities against selected pathogenic strains.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / pharmacology*
  • Bacillus / chemistry
  • Bacillus / classification
  • Bacillus / metabolism
  • Bacteria / chemistry
  • Bacteria / classification
  • Bacteria / drug effects
  • Bacteria / metabolism*
  • Microbial Sensitivity Tests
  • Saccharomyces cerevisiae / drug effects
  • Seawater / microbiology*
  • Streptomyces / chemistry
  • Streptomyces / classification
  • Streptomyces / metabolism
  • Water Microbiology*
  • Yeasts / drug effects*

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents