Breakthrough discoveries in drug delivery technologies: the next 30 years

Davide Brambilla; Paola Luciani; Jean-Christophe Leroux

doi:10.1016/j.jconrel.2014.03.056

Breakthrough discoveries in drug delivery technologies: the next 30 years

J Control Release. 2014 Sep 28:190:9-14. doi: 10.1016/j.jconrel.2014.03.056. Epub 2014 Apr 30.

Authors

Davide Brambilla¹, Paola Luciani¹, Jean-Christophe Leroux²

Affiliations

¹ Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland.
² Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland. Electronic address: jleroux@ethz.ch.

PMID: 24794899
DOI: 10.1016/j.jconrel.2014.03.056

Abstract

What if we could open the 2044 special issue of the Journal of Controlled Release? Which drug delivery technologies will have led the field? Which ones will have successfully reached the marketplace? In attempting to answer these questions, we selected a few recent technologies and concepts that could, in our opinion, play a crucial role in coming years. In each case, emblematic papers are cited to introduce and discuss the selected topic.

Keywords: Cell therapy; EPR effect; Microchips; Microneedles; Nanoparticles; Oncolytic viruses.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Biomedical Research / trends
Cell-Derived Microparticles
Delayed-Action Preparations*
Drug Delivery Systems / trends*
Forecasting*
Humans
Nanoparticles*
Oncolytic Virotherapy / trends

Substances

Delayed-Action Preparations