The impact of postsynaptic calcium on synaptic transmission--its role in long-term potentiation

Trends Neurosci. 1989 Nov;12(11):444-50. doi: 10.1016/0166-2236(89)90094-5.

Abstract

Recent studies have gone a long way to explain the steps involved in generating long-term potentiation (LTP). This review focuses on the triggering role of postsynaptic calcium, the sequence of events which might be initiated by calcium, and where the persistent change may ultimately occur during LTP.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Calcium / physiology*
  • Receptors, N-Methyl-D-Aspartate
  • Receptors, Neurotransmitter / physiology
  • Synapses / physiology*
  • Synaptic Membranes / physiology
  • Synaptic Transmission / physiology*
  • Time Factors

Substances

  • Receptors, N-Methyl-D-Aspartate
  • Receptors, Neurotransmitter
  • Calcium