New dimeric phthalides from Ligusticum sinense Oliv cv. Chaxiong

J Asian Nat Prod Res. 2014;16(7):747-52. doi: 10.1080/10286020.2014.914501. Epub 2014 Apr 29.

Abstract

A new dimeric phthalide, chaxiongnolide A (1), and a new natural product, chaxiongnolide B (2), together with a known compound Z-ligustilide (3), were isolated from the rhizome of Ligusticum sinense Oliv cv. Chaxiong. Their structures were elucidated by various spectroscopic methods and confirmed by X-ray crystallographic analysis.

Keywords: chaxiongnolide A; chaxiongnolide B; dimeric phthalides; Ligusticum sinense Oliv cv. Chaxiong.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Butyrolactone / analogs & derivatives
  • 4-Butyrolactone / chemistry
  • 4-Butyrolactone / isolation & purification
  • Benzofurans / chemistry
  • Benzofurans / isolation & purification*
  • Crystallography, X-Ray
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Ligusticum / chemistry*
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Rhizome / chemistry

Substances

  • Benzofurans
  • Drugs, Chinese Herbal
  • chaxiongnolide A
  • chaxiongnolide B
  • ligustilide
  • phthalide
  • 4-Butyrolactone