1-Acetyl-5-meth-oxy-4-(phenyl-sulfan-yl)imidazolidin-2-one

Joel T Mague; Alaa A-M Abdel-Aziz; Adel S El-Azab; Amer M Alanazi

doi:10.1107/S1600536814000117

1-Acetyl-5-meth-oxy-4-(phenyl-sulfan-yl)imidazolidin-2-one

Acta Crystallogr Sect E Struct Rep Online. 2014 Jan 15;70(Pt 2):o145-6. doi: 10.1107/S1600536814000117. eCollection 2014 Feb 1.

Authors

Joel T Mague¹, Alaa A-M Abdel-Aziz², Adel S El-Azab³, Amer M Alanazi⁴

Affiliations

¹ Department of Chemistry, Tulane University, New Orleans, LA 70118, USA.
² Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia ; Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura 35516, Egypt.
³ Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia ; Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
⁴ Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

Abstract

The title compound, C12H14N2O3S, crystallizes with two independent mol-ecules (A and B) in the asymmetric unit. The five-membered imidazolidin-2-one rings in both mol-ecules are twisted about the C-C bond. In the crystal, the A and B mol-ecules are associated via pairs of N-H⋯O hydrogen bonds, forming A-B dimers. These dimers are linked via C-H⋯S hydrogen bonds, forming double dimers, which are in turn linked via C-H⋯O hydrogen bonds forming two-dimensional networks lying parallel to (001). There are also C-H⋯π inter-actions present, which consolide the layers and link them, so forming a three-dimensional structure.