57Fe Mössbauer spectroscopy and electron paramagnetic resonance studies of human liver ferritin, Ferrum Lek and Maltofer®

I V Alenkina; M I Oshtrakh; Z Klencsár; E Kuzmann; A V Chukin; V A Semionkin

doi:10.1016/j.saa.2014.03.049

57Fe Mössbauer spectroscopy and electron paramagnetic resonance studies of human liver ferritin, Ferrum Lek and Maltofer®

Spectrochim Acta A Mol Biomol Spectrosc. 2014 Sep 15:130:24-36. doi: 10.1016/j.saa.2014.03.049. Epub 2014 Apr 8.

Authors

I V Alenkina¹, M I Oshtrakh², Z Klencsár³, E Kuzmann⁴, A V Chukin⁵, V A Semionkin¹

Affiliations

¹ Department of Physical Techniques and Devices for Quality Control, Institute of Physics and Technology, Ural Federal University, Ekaterinburg 620002, Russian Federation; Department of Experimental Physics, Institute of Physics and Technology, Ural Federal University, Ekaterinburg 620002, Russian Federation.
² Department of Physical Techniques and Devices for Quality Control, Institute of Physics and Technology, Ural Federal University, Ekaterinburg 620002, Russian Federation; Department of Experimental Physics, Institute of Physics and Technology, Ural Federal University, Ekaterinburg 620002, Russian Federation. Electronic address: oshtrakh@gmail.com.
³ Institute of Molecular Pharmacology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Pusztaszeri út 59-67, Budapest 1025, Hungary.
⁴ Institute of Chemistry, Eötvös Loránd University, Budapest, Hungary.
⁵ Department of Theoretical Physics and Applied Mathematics, Institute of Physics and Technology, Ural Federal University, Ekaterinburg 620002, Russian Federation.

PMID: 24762570
DOI: 10.1016/j.saa.2014.03.049

Abstract

A human liver ferritin, commercial Ferrum Lek and Maltofer® samples were studied using Mössbauer spectroscopy and electron paramagnetic resonance. Two Mössbauer spectrometers have been used: (i) a high velocity resolution (4096 channels) at 90 and 295K, (ii) and a low velocity resolution (250 channels) at 20 and 40 K. It is shown that the three studied materials have different superparamagnetic features at various temperatures. This may be caused by different magnetic anisotropy energy barriers, sizes (volume), structures and compositions of the iron cores. The electron paramagnetic resonance spectra of the ferritin, Ferrum Lek and Maltofer® were decomposed into multiple spectral components demonstrating the presence of minor ferro- or ferrimagnetic phases along with revealing marked differences among the studied substances. Mössbauer spectroscopy provides evidences on several components in the measured spectra which could be related to different regions, layers, nanocrystallites, etc. in the iron cores that coincides with heterogeneous and multiphase models for the ferritin iron cores.

Keywords: Electron paramagnetic resonance; Ferritin; Ferrum Lek; Maltofer®; Mössbauer spectroscopy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anisotropy
Electron Spin Resonance Spectroscopy*
Ferric Compounds / chemistry*
Ferritins / chemistry*
Humans
Iron / chemistry
Iron Isotopes / chemistry*
Liver / metabolism*
Magnetics
Microscopy, Electron, Scanning
Microscopy, Electron, Transmission
Organometallic Compounds / chemistry*
Polysaccharides / chemistry*
Reproducibility of Results
Spectroscopy, Mossbauer*
Temperature
X-Ray Diffraction

Substances

Ferric Compounds
Iron Isotopes
Organometallic Compounds
Polysaccharides
ferrum lek
Ferritins
Iron
teferrol