Dissipation rate and residue distribution of dufulin in tomato and soil under field conditions were investigated in Guiyang, Tianjin, and Haikou during 2011-2012, using ultra-performance liquid chromatography. Average recoveries of dufulin in tomato and soil ranged from 91.03 % to 95.16 % and 94.35 % to 98.34 %, respectively, with relative standard deviations of 1.16 %-3.97 %. Dufulin dissipation followed first-order kinetics. Dufulin had half-lives of 2.8, 4.7, and 9.0 days in tomato and 6.1, 8.2, and 17.2 days in soil in Guiyang, Tianjin, and Haikou, respectively. At harvest, dufulin residues in tomato samples collected 5 days after the last application at 3 times recommended dosage applied every 5 days were below 1.0 mg kg(-1).