EGFR-Driven Behavior and Intrapatient T790M Mutation Heterogeneity of Non-Small-Cell Carcinoma With Squamous Histology

J Clin Oncol. 2015 Nov 1;33(31):e115-8. doi: 10.1200/JCO.2013.49.5697. Epub 2014 Apr 21.

Authors

Paolo Graziano¹, Filippo de Marinis¹, Bruno Gori¹, Rita Gasbarra¹, Rita Migliorino¹, Stefano De Santis¹, Giuseppe Pelosi², Alvaro Leone³

Affiliations

¹ San Camillo-Forlanini Hospitals, Rome, Italy.
² Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto dei Tumori; and Università degli Studi, Milan, Italy.
³ San Camillo-Forlanini Hospitals, Rome, Italy aleone@scamilloforlanini.rm.it.

PMID: 24752053
DOI: 10.1200/JCO.2013.49.5697

No abstract available

Publication types

Case Reports

MeSH terms

Adenocarcinoma / diagnostic imaging
Adenocarcinoma / genetics
Adenocarcinoma / pathology
Aged
Carcinoma, Non-Small-Cell Lung / diagnostic imaging
Carcinoma, Non-Small-Cell Lung / genetics*
Carcinoma, Non-Small-Cell Lung / pathology
Carcinoma, Squamous Cell / diagnostic imaging
Carcinoma, Squamous Cell / genetics*
Carcinoma, Squamous Cell / pathology
DNA Mutational Analysis
Disease Progression
ErbB Receptors / genetics*
Exons
Female
Gene Deletion
Genetic Variation
Humans
Immunohistochemistry
Liver Neoplasms / diagnostic imaging
Liver Neoplasms / pathology
Liver Neoplasms / secondary
Lung Neoplasms / diagnostic imaging
Lung Neoplasms / genetics*
Lung Neoplasms / pathology
Middle Aged
Mutation*
Tomography, X-Ray Computed

Substances

EGFR protein, human
ErbB Receptors