Novel recombinant GII.P16_GII.13 and GII.P16_GII.3 norovirus strains in Italy

Virus Res. 2014 Aug 8:188:142-5. doi: 10.1016/j.virusres.2014.04.005. Epub 2014 Apr 19.

Abstract

Novel norovirus strains are continuously emerging worldwide. Molecular investigation and phylogenetic analysis identified GII.P16 recombinant noroviruses from the stools of four Italian children with gastroenteritis. The capsid gene was characterized as either GII.13 or GII.3. The GII.P16_GII.13 Italian strains were closely related to German strains involved in a large outbreak in the second half of 2012 and the Italian strains are the first recorded occurrence of GII.P16_GII.13 in Europe.

Keywords: GII.P16_GII.13; GII.P16_GII.3; Gastroenteritis; Italy; Norovirus; Recombination.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Caliciviridae Infections / virology
  • Capsid Proteins / genetics
  • Child, Preschool
  • Cluster Analysis
  • Gastroenteritis / virology
  • Genotype
  • Humans
  • Infant
  • Italy
  • Molecular Sequence Data
  • Norovirus / classification*
  • Norovirus / genetics*
  • Norovirus / isolation & purification
  • Phylogeny
  • RNA, Viral / genetics
  • Recombination, Genetic*
  • Sequence Analysis, DNA

Substances

  • Capsid Proteins
  • RNA, Viral

Associated data

  • GENBANK/KJ473823
  • GENBANK/KJ473824
  • GENBANK/KJ473825
  • GENBANK/KJ473826