Metal free synthesis of homoallylic alcohols promoted by ultrasound

Jucleiton José R Freitas; Túlio R Couto; Italo H Cavalcanti; Juliano C R Freitas; Roberta A Oliveira; Paulo H Menezes

doi:10.1016/j.ultsonch.2014.04.001

Metal free synthesis of homoallylic alcohols promoted by ultrasound

Ultrason Sonochem. 2014 Sep;21(5):1609-14. doi: 10.1016/j.ultsonch.2014.04.001. Epub 2014 Apr 12.

Authors

Jucleiton José R Freitas¹, Túlio R Couto¹, Italo H Cavalcanti¹, Juliano C R Freitas², Roberta A Oliveira¹, Paulo H Menezes³

Affiliations

¹ Departamento de Química Fundamental, Universidade Federal de Pernambuco, Recife, PE 50740-540, Brazil.
² Centro de Educação e Saúde, Universidade Federal de Campina Grande, Olho D'agua da Bica, s/n, Cuité, PB 58175-000, Brazil.
³ Departamento de Química Fundamental, Universidade Federal de Pernambuco, Recife, PE 50740-540, Brazil. Electronic address: paulo.menezes@pq.cnpq.br.

PMID: 24751290
DOI: 10.1016/j.ultsonch.2014.04.001

Abstract

The use of ultrasound irradiation to promote the allylation of aldehydes containing different functionalities with potassium allyltrifluoroborates is described. The method features the use of a minimum amount of acetone as solvent, without any other catalyst or promoter. The products were obtained in high yields, short reaction times, at room temperature and without the need of further purification.

Keywords: Allylation; Green chemistry; Potassium organotrifluoroborates.

Publication types

Research Support, Non-U.S. Gov't