Peeing pentraxins

Immunity. 2014 Apr 17;40(4):460-2. doi: 10.1016/j.immuni.2014.03.006.

Abstract

Antimicrobial agents secreted into urine potentially play a powerful role in the defense of the urinary tract. In this issue of Immunity, Jaillon et al. (2014) describe a role for pentraxin 3 molecules in complementing the host's cellular innate immune responses to uropathogens.

Publication types

  • Comment

MeSH terms

  • Animals
  • C-Reactive Protein / metabolism*
  • Escherichia coli / immunology*
  • Escherichia coli Infections / immunology*
  • Female
  • Humans
  • Neutrophils / immunology*
  • Pyelonephritis / immunology*
  • Receptors, Pattern Recognition / metabolism*
  • Serum Amyloid P-Component / metabolism*
  • Urinary Tract Infections / immunology*

Substances

  • Receptors, Pattern Recognition
  • Serum Amyloid P-Component
  • PTX3 protein
  • C-Reactive Protein