A 74-year-old female had previously undergone a left upper lobectomy and received radiotherapy for squamous cell carcinoma of the lung in 2002. She was admitted to our hospital because of left pulmonary aspergillosis in 2011. We performed left completion pneumonectomy and decortications. After the operation, Eikenella corrodens was isolated from pleural effusion. She was therefore diagnosed as having simultaneous empyema due to Eikenella corrodens, and continued to have antibiotic treatment. Wound dehiscence caused by malnutrition occurred postoperatively, but was healed by peroral nutritional support. She was discharged 78 days after the operation without recurrence of pulmonary aspergillosis and empyema for 23 months.