[Nosocomial infections after cardiac surgery in infants and children with congenital heart disease]

Rev Chilena Infectol. 2014 Feb;31(1):16-20. doi: 10.4067/S0716-10182014000100002.
[Article in Spanish]

Abstract

Introduction: Nosocomial infections generate high morbidity and mortality in children undergoing cardiac surgery.

Objective: To determine risk factors for nosocomial infections in children after congenital heart surgery.

Methods: A retrospective case-control study, in patients younger than 15 years undergoing surgery for congenital heart disease from January 2007 to December 2011 admitted to the Pediatric Critical Patient Unit (UPC-P) in a university hospital. For cases, the information was analyzed from the first episode of infection.

Results: 39 patients who develop infections and 39 controls who did not develop infection were enrolled. The median age of cases was 2 months. We identified a number of factors associated with the occurrence of infections, highlighting in univariate analysis: age, weight, univentricular heart physiology, complexity of the surgical procedure according to RACHS-1 and cardiopulmonary bypass (CPB) time ≥ 200 minutes. Multivariate analysis identified CPB time ≥ 200 minutes as the major risk factor, with an OR of 11.57 (CI: 1.04 to 128.5).

Conclusion: CPB time ≥ 200 minutes was the mayor risk factor associated with the development of nosocomial infections.

Publication types

  • English Abstract

MeSH terms

  • Child
  • Chile / epidemiology
  • Cross Infection / epidemiology*
  • Cross Infection / etiology
  • Female
  • Heart Defects, Congenital / surgery*
  • Humans
  • Infant
  • Intensive Care Units, Pediatric / statistics & numerical data*
  • Male
  • Multivariate Analysis
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / microbiology
  • Risk Factors