Four anti-inflammatory drugs induce tolC gene overexpression and repression of OmpF synthesis, enhance active efflux and decrease susceptibility to antibiotics in Escherichia coli AG100 strain

APMIS. 2014 Nov;122(11):1153-5. doi: 10.1111/apm.12273. Epub 2014 Apr 16.

Authors

María M Tavío¹, Virginia D Aquili, José B Poveda

Affiliation

¹ Microbiología, Departamento de Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad de Las Palmas de G.C, Las Palmas de G.C, Spain. mtavio@dcc.ulpgc.es.

PMID: 24735234
DOI: 10.1111/apm.12273

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology*
Anti-Inflammatory Agents / pharmacology*
Bacterial Outer Membrane Proteins / genetics*
Drug Resistance, Multiple, Bacterial / drug effects
Escherichia coli / drug effects*
Escherichia coli / genetics*
Escherichia coli Proteins / genetics*
Membrane Transport Proteins / genetics*
Porins / genetics*

Substances

Anti-Bacterial Agents
Anti-Inflammatory Agents
Bacterial Outer Membrane Proteins
Escherichia coli Proteins
Membrane Transport Proteins
OmpF protein
Porins
tolC protein, E coli