[Impact of HIV/AIDS on quality of life: meta-analysis 2002-2012]

Rev Esp Salud Publica. 2014 Jan-Feb;88(1):87-101. doi: 10.4321/S1135-57272014000100006.
[Article in Spanish]

Abstract

Background: HIV/AIDS is a chronic infection that transcends the biological domain and affects social relations, mental health, financial aspects and quality of life. The objective of the study was to assess the perception of Health Related Quality Of Life (HRQOL)) in people with HIV / AIDS.

Methods: Systematic review with meta-analysis. We applied a research protocol in four multidisciplinary databases: Pubmed, Science direct, Lilacs y Scielo; with search terms WHOQOL-BREF, WHOQOL-HIV-BREF, WHOQOLBREF-HIV. Quality assessment of articles was done by two researchers to ensure the completeness and reproducibility. HRQL was measured on a scale of 0 (worst outcome) to 100 points. The analysis was based on frequencies, summary measures, confidence intervals, and Student t test.

Results: The study included 19 studies with 3,348 people from 11 countries. The average of hrql was between 59 and 64 points, the lowest score was the environmental dimension with 59 points and the greater psychological health with 64 points. In the sensitivity analysis we found changes of 0 and 5 points between overall score and the observed data by excluding each individual study. We found good convergent validity on the dimensions common to both instruments evaluated, with differences of less than 3 points.

Conclusion: hrql scores in people with HIV/aids were good (greater than 50) which implies that proper management can reduce the negative effects on the physical health, psychological health, socials relations, the environment, independence level and spirituality.

Publication types

  • Meta-Analysis
  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / psychology
  • HIV Infections / psychology*
  • Health Status*
  • Humans
  • Quality of Life*
  • Reproducibility of Results
  • Sensitivity and Specificity