ERQC autophagy: Yet another way to die

Mol Cell. 2014 Apr 10;54(1):3-4. doi: 10.1016/j.molcel.2014.03.037.

Abstract

A novel autophagy pathway eliminates nonnative polytopic membrane proteins from the endoplasmic reticulum that evade degradation by the ubiquitin proteasome system.

Publication types

  • Comment

MeSH terms

  • Animals
  • Autophagy*
  • Cytosol / metabolism*
  • Endoplasmic Reticulum / metabolism*
  • Endoplasmic Reticulum-Associated Degradation*
  • Eukaryotic Cells / metabolism*
  • Humans
  • Protein Folding*
  • Proteins / metabolism*
  • Receptors, LHRH / metabolism*

Substances

  • GNRHR protein, human
  • Proteins
  • Receptors, LHRH