A new alkaloid glycoside from the rhizomes of Aristolochia fordiana

Nat Prod Res. 2014;28(14):1065-9. doi: 10.1080/14786419.2014.905934. Epub 2014 Apr 9.

Abstract

A new alkaloid glycoside named fordianoside (1), together with three known compounds arabinothalictoside (2), 6-O-p-coumaroyl-β-fructofuranosyl-(2 → 1)-α-d-glucopyranoside (3) and 4-[formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl] butanoic acid (4), was isolated from the rhizomes of Aristolochia fordiana. The structure of 1 was established as (1S)-1,2,3,4-tetrahydro-7-hydroxy-1-[(4-hydroxybenzyl) methyl]-2,2-dimethyl-8-O-isoquinolinyl β-d-glucopyranoside by using chemical and spectroscopic methods including HR-ESI-MS, 1D and 2D NMR.

Keywords: Aristolochia fordiana; Aristolochiaceae; alkaloid glycoside.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry
  • Alkaloids / isolation & purification*
  • Aristolochia / chemistry*
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Rhizome / chemistry*
  • Stereoisomerism

Substances

  • Alkaloids
  • Drugs, Chinese Herbal
  • Glucosides
  • Glycosides
  • arabinothalictoside
  • fordianoside