Diagnosis and counseling of fetal and neonatal HCMV infection

Early Hum Dev. 2014 Mar:90 Suppl 1:S29-31. doi: 10.1016/S0378-3782(14)70010-6.

Abstract

Fetal HCMV infection is investigated by amniocentesis when a maternal primary infection is diagnosed or ultrasound (US/MRI) abnormalities are observed. In fetal blood, prognostic markers of symptomatic congenital infection may be evaluated for parental counseling. At birth, viral load measurement in body fluids may correlate with long-term sequelae, but the prognostic accuracy of symptomatic infection increases when maternal, fetal, and neonatal parameters are combined.

Keywords: Congenital infection; HCMV; Prognostic markers.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amniocentesis
  • Biomarkers / blood
  • Biomarkers / urine
  • Counseling
  • Cytomegalovirus Infections / congenital
  • Cytomegalovirus Infections / diagnosis*
  • Female
  • Fetal Diseases / diagnosis*
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical
  • Pregnancy

Substances

  • Biomarkers