Abstract
Adding value to organic synthesis. Novel imine reductases enable the enantioselective reduction of imines to afford optically active amines. Likewise, novel bioinspired artificial metalloenzymes can perform the same reaction as well. Emerging proof-of-concepts are herein discussed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biocatalysis*
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Biotin / metabolism
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Imines / chemistry
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Imines / metabolism*
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Metalloproteins / metabolism*
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Oxidation-Reduction
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Oxidoreductases / metabolism*
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Stereoisomerism
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Streptavidin / metabolism
Substances
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Imines
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Metalloproteins
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Biotin
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Streptavidin
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Oxidoreductases