Asymptomatic bacteriuria in preadolescent girls

Rev Invest Clin. 2013 Sep-Oct;65(5):399-402.

Abstract

Background: The detection of asymptomatic bacteriuria in preadolescent girls may be important due to its effects on subsequent pregnancies.

Objective: To describe the prevalence of asymptomatic bacteriuria in preadolescent girls and the value of the nitrite test for screening.

Material and methods: Cross-sectional study in girls aged 9 to 13 years. Bacteriuria was defined as the growth of > 100,000 CFU/mL in 2 consecutive urine specimens.

Results: Three hundred and twenty seven girls were included. Asymptomatic bacteriuria was found in 7 girls, so the prevalence was 2.1% (95% CI, 1 to 4.4%). Escherichia coli was the isolated agent in all the cases. Focused interrogatory found history of urinary symptoms in 6 girls. The utility values of the nitrite test were: sensitivity, 1; specificity, 0.9; positive likelihood ratio, 10; and negative predictive value, 1.

Conclusions: The prevalence of asymptomatic bacteriuria in preadolescent girls in this Mexican study is similar to the one reported internationally; it is reasonable to consider its early detection to avoid its effects on future pregnancies. Nitrite test seems to be good for screening.

MeSH terms

  • Adolescent
  • Age of Onset
  • Asymptomatic Diseases
  • Bacteriuria / diagnosis
  • Bacteriuria / epidemiology*
  • Bacteriuria / urine
  • Child
  • Cross-Sectional Studies
  • Early Diagnosis
  • Escherichia coli / isolation & purification*
  • Escherichia coli Infections / diagnosis
  • Escherichia coli Infections / epidemiology*
  • Escherichia coli Infections / urine
  • Female
  • Humans
  • Mass Screening
  • Nitrites / urine
  • Nitrofurantoin / therapeutic use
  • Predictive Value of Tests
  • Prevalence
  • Puberty*
  • Reagent Strips
  • Treatment Failure

Substances

  • Nitrites
  • Reagent Strips
  • Nitrofurantoin