Can viscosupplementation be used in the hip? An Italian perspective

Orthopedics. 2014 Jan;37(1):48-55. doi: 10.3928/01477447-20131219-08.

Abstract

Viscosupplementation is the intra-articular administration of preparations containing hyaluronic acid or hyaluronate intended to restore the normal biological properties of hyaluronic acid normally found in synovial fluid. Infiltration of hyaluronic acid in the arthritic hip is a more recent technique than viscosupplementation of the knee due to the greater technical difficulty of infiltration to the hip, which requires fluoroscopic or ultrasound guidance. The introduction of high-molecular-weight hyaluronic acid in the treatment permits a single administration and has helped diffuse hip infiltration treatment. A single infiltration reduces patient discomfort caused by the procedure and allows treatment of a larger number of patients. Although the literature has unequivocally proven the possibility of reducing pain in patients affected by hip arthritis following infiltration, the molecular weight and density, the number of infiltrations required for long-term results, and the most appropriate indications for infiltration treatment have yet to be clarified. Selecting the patient is the first obstacle to be overcome. Therefore, infiltration should be considered as an option for patients with initial pain symptoms who have not yet been listed for joint prosthesis surgery. The radiographic criteria require at least a partly preserved joint space, and the clinical criteria of persistent hip pain and full joint mobility seem to be sufficiently effective for selection.

Publication types

  • Review

MeSH terms

  • Humans
  • Hyaluronic Acid / administration & dosage*
  • Hyaluronic Acid / adverse effects
  • Hyaluronic Acid / pharmacology
  • Injections, Intra-Articular / adverse effects
  • Injections, Intra-Articular / methods
  • Osteoarthritis, Hip / drug therapy*
  • Patient Selection
  • Synovial Fluid
  • Viscosupplementation / adverse effects
  • Viscosupplementation / methods
  • Viscosupplements / administration & dosage*
  • Viscosupplements / adverse effects
  • Viscosupplements / pharmacology

Substances

  • Viscosupplements
  • Hyaluronic Acid