Parvimonas micra as a causative organism of spondylodiscitis: a report of two cases and a literature review

Haruka Uemura; Kayoko Hayakawa; Kayo Shimada; Masayoshi Tojo; Maki Nagamatsu; Tohru Miyoshi-Akiyama; Saeko Tamura; Kazuhisa Mesaki; Kei Yamamoto; Yasuaki Yanagawa; Jun Sugihara; Satoshi Kutsuna; Nozomi Takeshita; Naoki Shoda; Akiyoshi Hagiwara; Teruo Kirikae; Norio Ohmagari

doi:10.1016/j.ijid.2014.02.007

Parvimonas micra as a causative organism of spondylodiscitis: a report of two cases and a literature review

Int J Infect Dis. 2014 Jun:23:53-5. doi: 10.1016/j.ijid.2014.02.007. Epub 2014 Mar 26.

Authors

Haruka Uemura¹, Kayoko Hayakawa², Kayo Shimada³, Masayoshi Tojo⁴, Maki Nagamatsu⁴, Tohru Miyoshi-Akiyama³, Saeko Tamura⁵, Kazuhisa Mesaki⁵, Kei Yamamoto², Yasuaki Yanagawa², Jun Sugihara², Satoshi Kutsuna², Nozomi Takeshita², Naoki Shoda⁶, Akiyoshi Hagiwara⁷, Teruo Kirikae³, Norio Ohmagari²

Affiliations

¹ Disease Control and Prevention Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan. Electronic address: ueueuemura@yahoo.co.jp.
² Disease Control and Prevention Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.
³ Department of Infectious Diseases, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
⁴ Disease Control and Prevention Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan; Department of Infectious Diseases, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
⁵ Department of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan.
⁶ Department of Orthopedic Surgery, National Center for Global Health and Medicine, Tokyo, Japan.
⁷ Department of Emergency Medicine and Critical Care, National Center for Global Health and Medicine, Tokyo, Japan.

PMID: 24680818
DOI: 10.1016/j.ijid.2014.02.007

Abstract

Spondylodiscitis caused by Parvimonas micra, a rarely reported infection, might be under-detected using conventional methods. This report of the detection and treatment of two cases of spondylodiscitis due to P. micra and review of the literature indicates that the use of gene sequencing methods might improve the accuracy of diagnosing this infection.

Keywords: 16S rRNA gene sequencing; Anaerobic bacteria; Parvimonas micra; Peptostreptococcus micros; Spondylodiscitis.

Publication types

Case Reports
Review

MeSH terms

Aged
Aged, 80 and over
Databases, Factual
Discitis / diagnosis*
Discitis / microbiology*
Female
Fusobacterium nucleatum / isolation & purification
Gram-Negative Bacteria / isolation & purification
Gram-Positive Cocci / isolation & purification*
Humans
Magnetic Resonance Imaging
Male
RNA, Ribosomal, 16S / genetics
Tomography Scanners, X-Ray Computed

Substances

RNA, Ribosomal, 16S