Externalization of tunneled hemodialysis catheter in patients with tunnel or exit-site infections and limited access options

J Vasc Interv Radiol. 2014 Apr;25(4):561-6. doi: 10.1016/j.jvir.2013.12.570.

Abstract

Purpose: To evaluate the viability and effectiveness of temporary externalization of a tunneled hemodialysis (HD) catheter in catheter-dependent HD patients presenting with catheter-related tunnel or exit-site infection, documented central venous stenosis, and limited alternative venous access.

Materials and methods: All catheter-dependent HD patients with known central venous stenosis presenting with exit-site or tunnel infection and who subsequently underwent catheter externalization between February 2008 and May 2012 were reviewed. After catheter externalization, patients were concurrently treated with antibiotics for approximately 3 weeks before reinsertion of a new tunneled catheter. Treatment outcomes were collected, with treatment failures defined as reinfection with the same organism within 45 days of tunneled catheter reinsertion.

Results: There were 42 catheter externalization procedures performed in 26 patients for 42 exit-site or tunnel infections. Technical success rate for catheter externalization was 100%, with no complications during the externalization procedure and preservation of all original access sites. Treatment failure occurred in 9.8% (4 of 41) of cases. Median infection-free survival after treatment and retunneling of a new dialysis catheter was 80 days. One major periprocedural complication of death occurred before reinsertion of a new tunneled catheter. Minor complications after the procedure occurred in four patients and included three cases of a small persistent wound at the temporary supraclavicular access site and one initially nonfunctioning externalized catheter.

Conclusions: Temporary dialysis catheter externalization appears both technically feasible and effective for the treatment of exit-site and tunnel infections, while allowing preservation of the venous access site in catheter-dependent HD patients with central venous stenosis and limited alternative venous access.

MeSH terms

  • Adult
  • Aged
  • Angioplasty, Balloon
  • Anti-Bacterial Agents / administration & dosage
  • Catheter Obstruction*
  • Catheter-Related Infections / diagnosis
  • Catheter-Related Infections / microbiology
  • Catheter-Related Infections / mortality
  • Catheter-Related Infections / therapy*
  • Catheterization, Central Venous* / adverse effects
  • Catheterization, Central Venous* / instrumentation
  • Catheterization, Central Venous* / mortality
  • Catheters, Indwelling / adverse effects*
  • Central Venous Catheters / adverse effects*
  • Combined Modality Therapy
  • Constriction, Pathologic
  • Device Removal
  • Female
  • Humans
  • Male
  • Middle Aged
  • Recurrence
  • Renal Dialysis* / adverse effects
  • Renal Dialysis* / instrumentation
  • Renal Dialysis* / mortality
  • Retrospective Studies
  • Therapeutic Irrigation
  • Time Factors
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents