Cytokines in patients with type 2 diabetes and chronic periodontitis: A systematic review and meta-analysis

Momen A Atieh; Clovis M Faggion Jr; Gregory J Seymour

doi:10.1016/j.diabres.2014.02.002

Cytokines in patients with type 2 diabetes and chronic periodontitis: A systematic review and meta-analysis

Diabetes Res Clin Pract. 2014 May;104(2):e38-45. doi: 10.1016/j.diabres.2014.02.002. Epub 2014 Mar 3.

Authors

Momen A Atieh¹, Clovis M Faggion Jr², Gregory J Seymour³

Affiliations

¹ Sir John Walsh Research Institute, Department of Oral Sciences, School of Dentistry, University of Otago, Dunedin, New Zealand. Electronic address: maatieh@gmail.com.
² Sir John Walsh Research Institute, Department of Oral Sciences, School of Dentistry, University of Otago, Dunedin, New Zealand; Department of Periodontology, Faculty of Dentistry, University of Münster, Münster, Germany.
³ Sir John Walsh Research Institute, Department of Oral Sciences, School of Dentistry, University of Otago, Dunedin, New Zealand.

PMID: 24655616
DOI: 10.1016/j.diabres.2014.02.002

Abstract

Individuals with type 2 diabetes mellitus (T2DM) and chronic periodontitis have significantly higher levels of interleukin-1 beta compared with systemically healthy individuals with chronic periodontitis. However, there was no significant difference in gingival crevicular levels of other cytokines between individuals with and without T2DM.

Keywords: Cytokines; Inflammation; Interleukin; Meta-analysis; Systematic review.

Publication types

Meta-Analysis
Review
Systematic Review

MeSH terms

Biomarkers / metabolism
Chronic Periodontitis / complications
Chronic Periodontitis / metabolism*
Cytokines / metabolism*
Diabetes Mellitus, Type 2 / complications
Diabetes Mellitus, Type 2 / metabolism*
Gingival Crevicular Fluid / metabolism
Humans

Substances

Biomarkers
Cytokines