Chemotherapy or radiation-induced oral mucositis

Rajesh V Lalla; Deborah P Saunders; Douglas E Peterson

doi:10.1016/j.cden.2013.12.005

Chemotherapy or radiation-induced oral mucositis

Dent Clin North Am. 2014 Apr;58(2):341-9. doi: 10.1016/j.cden.2013.12.005.

Authors

Rajesh V Lalla¹, Deborah P Saunders², Douglas E Peterson³

Affiliations

¹ Section of Oral Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-1605, USA. Electronic address: Lalla@uchc.edu.
² Department of Dental Oncology, Northeast Cancer Centre, Health Sciences North, Northern Ontario School of Medicine, 41 Ramsey Lake Road, Sudbury, ON P3E 5J1, Canada.
³ Section of Oral Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-1605, USA.

PMID: 24655526
DOI: 10.1016/j.cden.2013.12.005

Abstract

Oral mucositis is a significant toxicity of systemic chemotherapy and of radiation therapy to the head and neck region. The morbidity of oral mucositis can include pain, nutritional compromise, impact on quality of life, alteration in cancer therapy, risk for infection, and economic costs. Management includes general symptomatic support and targeted therapeutic interventions for the prevention or treatment of oral mucositis. Evidence-based clinical practice guidelines are available to guide clinicians in the selection of effective management strategies.

Keywords: Cancer; Chemotherapy; Oral mucositis; Radiation therapy; Stomatitis.

Publication types

Review

MeSH terms

Antineoplastic Agents / adverse effects*
Cost of Illness
Humans
Nutrition Disorders / etiology
Pain / etiology
Patient Care Planning
Practice Guidelines as Topic
Quality of Life
Radiotherapy / adverse effects*
Stomatitis / chemically induced*
Stomatitis / etiology
Stomatitis / therapy

Substances

Antineoplastic Agents