Abstract
A water-soluble, charge-switchable, four-armed polymeric photosensitizer (C4P-PS), in which charge switching is pH dependent, has been designed as a new class of photosensitizer for photodynamic cancer therapy.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cell Survival / drug effects
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HCT116 Cells
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Humans
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Hydrogen-Ion Concentration
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Lasers
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Mice
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Mice, Nude
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Neoplasms / drug therapy
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Photochemotherapy
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Photosensitizing Agents / chemistry*
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Photosensitizing Agents / pharmacology
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Photosensitizing Agents / therapeutic use
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Polymers / chemistry*
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Porphyrins / chemistry*
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Porphyrins / pharmacology
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Porphyrins / therapeutic use
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Transplantation, Heterologous
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Water / chemistry
Substances
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C4P-PS compound
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Photosensitizing Agents
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Polymers
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Porphyrins
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Water