Multimodal luminescent-magnetic boron nitride nanotubes@NaGdF₄:Eu structures for cancer therapy

Chem Commun (Camb). 2014 Apr 28;50(33):4371-4. doi: 10.1039/c4cc00990h.

Abstract

Boron nitride nanotubes@NaGdF4:Eu composites with core@shell structures were fabricated giving the opportunity to trace, target and thus to manipulate BNNTs in vitro. The composites show a significantly higher cellular uptake and chemotherapy drug intracellular delivery ability in the presence of an external magnetic field than that in its absence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / therapeutic use
  • Antineoplastic Agents / toxicity
  • Boron Compounds / chemistry*
  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Doxorubicin / chemistry
  • Doxorubicin / therapeutic use
  • Doxorubicin / toxicity
  • Drug Carriers / chemistry
  • Humans
  • Magnetic Fields
  • Nanostructures / chemistry*
  • Nanotubes / chemistry*
  • Neoplasms / drug therapy
  • Neoplasms / radiotherapy

Substances

  • Antineoplastic Agents
  • Boron Compounds
  • Drug Carriers
  • boron nitride
  • Doxorubicin