DNA from natural sources in design of functional devices

Methods. 2014 May 15;67(2):105-15. doi: 10.1016/j.ymeth.2014.03.003. Epub 2014 Mar 12.

Abstract

The role of DNA as structuring or templating agent has become more significant with the development of nanobiotechnology. Although short single and double stranded DNA have extensively been used as immobilization tool, as a template for nanoparticle preparation and in design of various devices such as nanomotors and biosensors, DNA from natural sources has an advantage of being abundant, cheap and readily available. Therefore, it is not surprising that there is a huge interest in making the use of natural DNA properties for both nano- and micro-applications. In this review we attempt to give an overview of the up to date applications of natural DNA, either from viral, marine or mammalian sources, in design of functional devices. This article is meant to be a starting point and a guide to the platforms in which natural DNA is employed such as DNA origami, optoelectronic devices and organic catalysis.

Keywords: DNA in organic catalysis; DNA origami; DNA thin films; Optoelectronics; Salmon sperm DNA; Viral DNA.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alkylation
  • Animals
  • Catalysis
  • Cycloaddition Reaction
  • DNA / chemistry
  • DNA / ultrastructure
  • DNA, Catalytic / chemistry*
  • Humans
  • Nanoparticles / chemistry*
  • Nanoparticles / ultrastructure
  • Nucleic Acid Amplification Techniques
  • Nucleic Acid Conformation
  • Optics and Photonics

Substances

  • DNA, Catalytic
  • DNA