Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock

Front Med. 2014 Jun;8(2):254-8. doi: 10.1007/s11684-014-0319-1. Epub 2014 Mar 14.

Abstract

Mantle cell lymphoma is an aggressive subtype of B cell non-Hodgkin lymphoma. It can progress to leukemic phase but frank leukemic picture at initial presentation is not common. Leukemic phase indicates advance stage of the disease and generally associated with extensive extra-nodal involvement. Pericardial invasion has been reported, however we could not find a report of myocardial infiltration by this disease since the appraisal of the term "mantle cell lymphoma" in 1992. Here we report a case of cardiac involvement by mantle cell leukemia leading to cardiogenic shock which complicates the treatment decisions.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Female
  • Humans
  • Lymphoma, Mantle-Cell / complications*
  • Lymphoma, Mantle-Cell / diagnosis
  • Lymphoma, Mantle-Cell / drug therapy
  • Lymphoma, Mantle-Cell / pathology
  • Middle Aged
  • Myocardium / pathology
  • Shock, Cardiogenic / etiology*

Substances

  • Antineoplastic Agents