Abstract
NIS-mediated iodocyclization of N-sulfonyl propargylamides for the synthesis of various oxazolidines and iodoalkylidenedihydrooxazoles via a 5-exo-dig process is developed. The resulting iodoalkylidenedihydrooxazoles can be further transformed into the corresponding oxazoles in the presence of dioxygen.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Crystallography, X-Ray
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Cyclization
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Molecular Structure
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Oxazoles / chemical synthesis*
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Oxazoles / chemistry*
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Oxidation-Reduction
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Oxygen / chemistry*
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Pargyline / analogs & derivatives*
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Pargyline / chemistry*
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Succinimides / chemistry*
Substances
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Oxazoles
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Succinimides
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N-iodosuccinimide
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Pargyline
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Oxygen